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(1970) Microbial conver-sion of dithiocarbamate fungicides.

10, 1998 SEARCH FOR NEW DRUGS SYNTHESIS AND ANTIOXIDANT ACTIVITY OF DITHIOCARBAMATES BASED ON ALIPHATIC DIAMINES M.

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(1962) Chemistry and mode of actionof dithiocarbamate fungicides.

Glucuronic acidconjugation might be overloaded after the administration ofdiethyldithiocarbamate but not after the administration ofdisulfiram, which is taken up by the liver at a much slowerrate.

Wuts, Protecting Groups in Organic Synthesis, 3rd ed., Wiley Interscience, New York, 1999, pp.

Figure 2: Structures of dithiocarbamates with anti cancer activity Recently, Brassinin (figure 3), a dithiocarbamate isolated from cabbage, was reported to have anticancer activity, and its structural modification led to the design and synthesis of a potential cancer chemopreventive agent (4-methanesulfinyl-butyl)-dithiocarbamic acid methyl ester (Sulforamate).


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SYNTHESIS OF DITHIOCARBAMATES AND …

Zhou, Facile synthesis of novel ionic liquids containing dithiocarbamate, Synth.

12 the sum of manco- page 137 zeb, maneb, and zineb) 1977 0-0.005 1978b (temporary) (sum of manco- 1978a zeb, maneb, and zineb) 1974 0-0.005 1975b (temporary) (sum of all di- 1975a thiocarbamates) 1970 0-0.025 1971b (temporary) (applicable to the 1971a parent compound only, and to the sum of all the di- thiocarbamate fung- icides if more than one is present) 1967 0-0.025 1968b (temporary) (alone or in com- 1968a bination with other ethylene bisdithiocarbamates (mancozeb and zineb) including zineb derived from nabam plus zinc sulfate)--------------------------------------------------------------------------------------------------------Annex III.

(contd.)--------------------------------------------------------------------------------------------------------Compound Year ADIb Evaluation IARCd Availability WHO recom- WHO/FAO of (mg/kg by JMPRc: Evaluation of IRPTCe: mended clas- Data JMPR body Published of Carcino- Data Legal sification Sheets meet- weight) in: genicity Profile fileg of pesticides on Pest- ing FAO/WHO by hazardh icidesf --------------------------------------------------------------------------------------------------------Mancozeb 1983 0-0.05i 1984a + + 0 1980 0-0.05i (indivi- 1981b dually of the sum 1981a of mancozeb, maneb, and zineb) 1977 0-0.005 1978b (temporary) (sum of mancozeb, 1978a maneb, and zineb) 1974 0-0.005 1975b (temporary) (sum of dithio- 1975b carbamates) 1975b 1975a 1970 0-0.025 1971b (temporary) (applicable to the 1971a parent compound only, and the sum of all the ethylene bisdithiocarbamate fungicides if more than one is present) 1967 0-0.025 1968b (temporary) (alone or in com- 1968a bination with other ethylene bisdithiocarbamates (maneb and zineb), including zineb derived from nabam plus zinc sulfate)--------------------------------------------------------------------------------------------------------Annex III.

One-Pot Synthesis of Dithiocarbamates Accelerated in Water

(1965) Metabolism of disulfiram and diethyl-dithiocarbamate in rats with demonstration of an in vivoethanol-induced inhibition of the glucuronic acid conjugation ofthe thiol.

(contd.)--------------------------------------------------------------------------------------------------------Compound Year ADIb Evaluation IARCd Availability WHO recom- WHO/FAO of (mg/kg by JMPRc: Evaluation of IRPTCe: mended clas- Data JMPR body Published of Carcino- Data Legal sification Sheets meet- weight) in: genicity Profile fileg of pesticides on Pest- ing FAO/WHO by hazardh icidesf --------------------------------------------------------------------------------------------------------Maneb 1965 no ADI 1965b(contd.) 1965a 1963 no ADI 1964Nabam 1983 no ADI 1984a + + II 1977 no ADI 1978b 1978a 1974 0-0.005 1975b (temporary) (sum of all di- 1975a thiocarbamates) 1970 0-0.025 1971b (temporary) (applicable to the 1971a parent compound only, and to the sum of all the di- thiocarbamate fung- icides if more than one is present) 1967 0-0.025 1968b (temporary) (as nabam alone 1968a or in combination with other ethylene bisdithiocarbamates (mancozeb, maneb, and zineb) including zineb derived from nabam plus zinc sulfate) 1965 no ADI 1965b 1965a 1963 no ADI 1964--------------------------------------------------------------------------------------------------------Annex III.

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  • Synthesis of S -difluoromethyl dithiocarbamates, …

    General Dithiocarbamates are mainly used in agriculture as insecti-cides, herbicides, and fungicides.

  • One-Pot Synthesis of Dithiocarbamates Accelerated In …

    Wenzler, et al., Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1H-1,2,3-triazoles, J.

  • PRACTICAL SYNTHESIS OF AROMATIC DITHIOCARBAMATES …

    Zhang, Highly efficient catalyst-free one-pot synthesis of dithiocarbamates under solvent-free conditions, Chin.

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Synthesis and spermicidal activities of dithiocarbamates

(1977) Effects of food processing on residues of ethylene bisdithiocarbamate fungicides and ethylenethiourea, Washington DC, US EnvironmentalProtection Agency (EPA No.

Synthesis and Reactions of Heterocyclic Dithiocarbamates

(1973) Protec-tion by diethyldithiocarbamate against carbon tetrachloridelethality in rats and against carbon tetrachloride-induced lipidperoxidation in vitro.

C-N Bond Formation - Organic chemistry

(1971) [Reduction of the toxicity to theliver of carbon tetrachloride by diethyldithiocarbamate and 3-(O-tolyl)-4-(nitro)-sydnone.] Acta biol.

Ester synthesis by esterification - Organic chemistry

(1980) Some public health aspects of the manufacture and use of zinc and manganese ethylenebisdithiocarbamate fungicides Poznan, Poland, InstitutOchrony Roslin, February 1979 pp.

Thieme E-Books & E-Journals - Synthesis / Issue

(1974) Rapidformation of carcinogenic N-nitrosamines by interaction ofnitrite with fungicides derived from dithiocarbamic acid in vitro under simulated gastric conditions and in vivo in the ratstomach.

Chemistry - Home - :: Lucknow University

SOURCES OF HUMAN AND ENVIRONMENTAL EXPOSURE During recent years, much attention has been paid to thefinding that ETU may occur in plant samples following the use ofdithiocarbamate fungicides.

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