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Chinese Journal of Synthetic Chemistry, 2016, 24(1): 79-83.

Acid-catalysed rearrangement ofthe product in methanol occurs readily with the formation of methyl 4,5-dioxohexanoate.

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Chinese Journal of Synthetic Chemistry, 2016, 24(1): 16-20.

Stewart RD & Dodd HC (1964) Absorption of carbon tetrachloride, trichloroethylene, tetrachloroethylene, methylene chloride, and 1,1,1-trichloroethane through the human skin.

(1992) described the remediation of ground water contaminated with dichloromethane after a leak.

Dillon DM, Combos RD, McConville M, & Zeiger E (1990) The role of metabolism and glutathione in the mutagenicity of vapour phase dichloromethane in bacteria.

Howard PH (1990) Dichloromethane.

It is also used as a releasing agent in the moulding of polyurethane products.

ECETOC (1989) Methylene chloride (dichloromethane): an overview of experimental work investigating species, differences in carcinogenicity and their relevance to man.

Dillon DM, Edwards IR, Combos RD, McConville M, & Zeiger E (1992) The role of glutathione in the bacterial mutagenicity of vapor phase dichloromethane.

Studies on the exposure of rats and mice to dichloromethane.

Methanogenesis of mixed rumen microflora was inhibited from 136 mg/litre (Bauchop, 1967).

Blum & Speece (1991) determined the toxicity of methylene chloride to methanogenic bacteria and found an IC50 for inhibition of gas production of 7.2 mg/litre.

7.2.1 Plants The EC50 for Lemna minor growth was 2000 mg/litre, whilst both growth and photosynthesis of the plant Groenlandia densa were totally inhibited at this concentration after 7 days (Merlin et al., 1992).

Workers in this study were also reported to have been exposed to methanol and acetone.
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  • US EPA (1980) Ambient water quality criteria for halomethanes.

    Methyl chloride is first produced by the reaction of methanol with hydrogen chloride and is then reacted with chlorine.

  • US EPA (1981) Environmental risk assessment of dichloromethane.

    Other halomethanes were also found and measured in the samples at average concentrations ranging from 9 to 25 µg/litre.

  • Synthesis of 2- and 3-acetylfuran carbethoxyhydrazones …

    Similar increases were seen in rats pretreated with a single garage dose of methanol (Pankow & Jagielki, 1993).

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Synthesis and Characterization of 2- Acetyl Furan …

Masuda Y, Yano I, & Murano T (1980) Comparative studies on the hepatoxic actions of chloroform and related halogenomethanes in normal and phenobarbital-pretreated animals.

24/06/2017 · Synthesis of AFBH

Mattsson JL, Albee RR, & Eisenbrandt DL (1990) Neurotoxicologic evaluation of rats after 13 weeks of inhalation exposure to dichloromethane or carbon monoxide.

Get supplier listing of 5-Methyl-2-acetylfuran and equal product

Kurppa K & Vainio H (1981) Effects of intermittent dichloromethane inhalation on blood carboxyhaemoglobin concentration and drug metabolizing enzymes in rat.

12/01/2018 · Synthesis of (L) -daunosamine and ..

Kurppa K, Kivisto H, & Vainio H (1981) Dichloromethane and carbon monoxide inhalation: carboxyhaemoglobin addition and drug metabolising enzymes in rat.

Asymmetric reduction of 2-acetylfuran (5) ..

Kramers PGN, Mout HCA, Bissumbhar B, & Mulder CR (1991) Inhalation exposure in Drosophila mutagenesis assays: experiments with aliphatic halogenated hydrocarbons, with emphasis on the genetic activity profile of 1,2-dichloroethane.


Kirschman JC, Brown NM, Coots RH, & Morgareidge K (1986) Review of investigations of dichloromethane metabolism and subchronic oral toxicity study as the basis for the design of chronic oral studies in rats and mice.

Synthesis and methylation products of 4(5)-(2 …

Mennear JH, McConnell EE, Huff JE, Renne RA, & Giddens E (1988) Inhalation toxicology and carcinogenesis studies of methylene chloride (dichloromethane) in F344/N rats and B6C3F1 mice.

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