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One-pot three-enzyme synthesis of UDP-GlcNAc derivatives

One-pot three-Enzyme Synthesis of UDP-GlcNAc Derivatives

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for 100 mg scale synthesis of UDP-Gal, UDP-GlcNAc, ..

AB - A Pasteurella multocida N-acetylglucosamine 1-phosphate uridylyltransferase (PmGlmU) was cloned and used efficiently with an N-acetylhexosamine 1-kinase (NahK-ATCC55813) and an inorganic pyrophosphatase (PmPpA) for one-pot three-enzyme synthesis of UDP-GlcNAc derivatives with or without further chemical diversification.

Figure 4 shows the one-pot three-enzyme synthesis of UDP-GlcNAc and ..

A Pasteurella multocida N-acetylglucosamine 1-phosphate uridylyltransferase (PmGlmU) was cloned and used efficiently with an N-acetylhexosamine 1-kinase (NahK-ATCC55813) and an inorganic pyrophosphatase (PmPpA) for one-pot three-enzyme synthesis of UDP-GlcNAc derivatives with or without further chemical diversification.

USPs in large scale synthesis of UDP-sugar and derivatives

Nevertheless, chemoenzymatic synthesis of UDP-GlcNAc derivatives using all …

N2 - A Pasteurella multocida N-acetylglucosamine 1-phosphate uridylyltransferase (PmGlmU) was cloned and used efficiently with an N-acetylhexosamine 1-kinase (NahK-ATCC55813) and an inorganic pyrophosphatase (PmPpA) for one-pot three-enzyme synthesis of UDP-GlcNAc derivatives with or without further chemical diversification.

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Synthetic receptors for high-affinity recognition of O-GlcNAc derivatives ..
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