19-12-2017 · Microwave-Assisted Synthesis of ..
One-pot synthesis of novel 1,1′- and 1,4-bridged bis-thiazolidinone derivatives and their antimicrobial activity.
of Schiff Base Derivatives of 5-(2-Phenoxypyridin-3-yl)-1 ..
Himaja, Ramana M.V, Sikarwar Mukesh, One-Pot Synthesis And Antimicrobial Activity Of 2-Amino-5-Aryl-5h-Thiazolo [4,3-B]-1,3,4-Thiadiazoles, International Journal of Research in Ayurveda and Pharmacy 2011; 2 (1) : 170-174
1Dictated by the previous research results of thiazolidinone derivatives, the aim of the presented work was to synthesize new 2,3,5-trisubstituted 4-thiazolidinones bearig an isatin fragment and to investigate their anticancer activity.
The reaction of nitriles with mercaptoacetic acid
The reaction between 2,6-dimethylphenyl isocyanide, 1,3-cyclohexanediones and DMAD provided a simple one-pot entry into the synthesis of polyfunctional 4-chromene derivatives (Scheme ).
Archana , Srivastava, V.K.; Kumar, A, Synthesis of newer thiadiazolyl and thiazolidinonyl quinazolin-4(3H)- ones as potential anticonvulsant agents, European Journal of Medicinal Chemistry, 37, 2002, , 873-882.
Fung Fuh Wong, An efficient one-pot synthesis of N-(1,3-diphenyl ..
Fuloria, Synthesis and antimicrobial profile of newer schiff bases and thiazolidinones derivatives" World Academy of Science Engineering and Technology 2014, 8,12, 1228-1231.
Recently a series of 2-amino-5-sulfanyl-1,3,4-thiadiazole derivatives bearing different substituents were synthesized and screened pharmacologically in order to evaluate their central nervous system activity. The purpose of this study was to evaluate the effects of the title compounds on CNS activity by varying the substituents in the thiadiazole moiety. It was found that some of these compounds possess marked antidepressant and anxiolytic properties comparable in efficiency to the reference drugs Imipramine and Diazepam. The most potent compound 3k was further investigated to complete its pharmacological profile with respect to undesired side effects. Behavioral results showed that 3k is a very promising compound, characterized by a mixed antidepressant-anxiolytic activity accompanied by a therapeutic dose range that is essentially 2 orders of magnitude less than that at which side effects such as sedation and amnesia are evident.
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PDF Downloads : Oriental Journal of Chemistry
One-Pot Synthesis of 1,3-Thiazolidin-4-Ones Derivatives from 2-Amino-1,3,4-Thiadiazole.
BACHELOR OF PHARMACY (HONS) - AIMST University
Synthesis and biological evaluation of new 1,3-thiazolidine-4-one derivatives ..
Journal of Heterocyclic Chemistry ..
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