Core D also synthesizes glycans for and prints the CFG glycan array.
If you have any questions about these changes, please email the Protein-Glycan Interaction Core at .
Core H - Glycan Array Screening
When a request is approved by the Steering Committee, the Protein-Glycan Interaction Core will still send the PI an email, which will now contain the instructions for proceeding to the website and entering sample information.
With this as a base, the SC and the individual cores, alone or in combination, will consider alternate funding to continue expansion and development of resources and databases, and offer resources at lower cost
How do I use the Consortium for Functional Glycomics (CFG) search function?
To search for all CFG-related information, data, resource requests, and editorial content pertaining to a particular carbohydrate or glycan-binding protein, simply type the name into the search box on the using a keyword (e.g.
terminal sequences in the context of the different core structures
"This technology allows researchers to assay hundreds of carbohydrate varieties in a single experiment," Berg said. "The glycan microarray offers a detailed picture of viral receptor specificity that can be used to map the evolution of new human pathogenic strains, such as the H5N1 avian influenza, and could prove invaluable in the early identification of emerging viruses that could cause new epidemics."
Members of the consortium tested the new microarray on a variety of glycan binding proteins from humans and other organisms. They also looked at the carbohydrate binding properties of a complete virus, which suggests that the arrays may be able to define the carbohydrate-binding specificity for whole viruses as well as viral proteins.
Fucosyltransferases as Synthetic Tools: Glycan Array …
The glycan microarray technology, which was used to identify the mutations that could enable adaptation of H5N1 into the human population in the laboratory, could also be used to help identify new active virus strains in the field by monitoring changes in the receptor binding preference profile where infection is active, according to Jeremy M. Berg, the director of the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health (NIH). The glycan microarray was developed by The Consortium for Functional Glycomics, an international group led by Scripps Research scientists and supported by the NIGMS.
Other authors of the study include James Stevens of Scripps Research; Ola Blixt of Scripps Research and Glycan Array Synthesis Core-D, Consortium for Functional Glycomics; Terrence M. Tumpey, Influenza Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention; Jeffery K. Taubenberger, Department of Molecular Pathology, Armed Forces Institute of Pathology, and; James C. Paulson, Scripps Research and Glycan Array Synthesis Core-D, Consortium for Functional Glycomics.
Glycan Array Synthesis Core (D), ..
Here we demonstrate that glycan microarrays can be ..
The policy stipulates that data generated by CFG-funded Scientific Cores are input directly into the CFG databases.
Glycan Arrays | Dna Microarray | Proteins
At the discretion of the Mouse Subcommittee, Core G also occasionally evaluates mouse lines provided by investigators.
core-monosaccharide of a fucosylated N-glycan is also ..
The appropriate core director will review your request and contact you if more information is needed.
Novel Fluorescent Glycan Microarray Strategy Reveals ..
"This array covers all the major types of terminal sugars," says Paulson. He notes that for the majority of glycan structures, their "inner core" portion, is the same in all cells and tissues. What varies are the terminal sequences of sugars, the last few end sugars on the carbohydrate chain. Proteins that bind to carbohydrates only recognize the last few sugars in a carbohydrate chain, and perhaps as few as 500 or so of these terminal sequences in nature are relevant.
irrespective of the core glycan ..
Glycan Array Synthesis Core (D), located at The Scripps Research Institute, produces and collects carbohydrate compounds (monosaccharides, disaccharides, etc.), glycan-binding proteins ...
on the CFG glycan array, because of their difficult synthesis.
When publications are planned involving resources from or collaborations with a Scientific Core, the investigator is responsible for determining (at the earliest possible stage) if Core member(s) should be co-author(s).
Core Shared Facilities - University of California, San Diego
Core D also synthesizes glycans for and prints the CFG glycan array (see Core H below) Gene Microarray Core (E), located at The Scripps Research Institute ...
Find information on core shared research facilities at UC San Diego
If an investigator's lab conducts joint experiments with a Core, it should be assumed that the experiments are being done collaboratively unless otherwise agreed with the Core Director to be an established protocol of the Core.
Glycan Array Screening at the Protein-Glycan ..
Once the core director finalizes your request and makes a recommendation, the CFG Steering Committee will review it for final approval at their next bi-weekly meeting.
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