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Folate: dietary supplement fact sheet.

Folic Acid Deficiency Anemia.

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Folate (as Folic Acid) 400µg (200% NRV)

Ingredients: Vega Base™ (Acacia Gum, Fruit Juice Concentrates (Aronia, Apple, Elderberry, Blueberry & Blackcurrant), Vegetarian Capsule Shell (Hydroxypropyl Methylcellulose, Colours (Titanium Dioxide, Copper Chlorophyllin)), Anti-caking Agent (Magnesium Stearate), Folic Acid

VEGA Folic Acid is a high-strength supplement that provides 400µg of folate per single capsule.

Recent research has shown that folic acid may be beneficial for the heart. Heavy drinkers, individuals with a poor appetite or diet, menstruating and pregnant women, infants, adolescents and those with a mentally or physically demanding lifestyle may have an increased dietary requirement for folic acid.

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-take steroids or oral contraceptive pills

-have kidney disease

-have an overactive thryoid

-eat a lot of protein
You may need more if you....
B Vitamins
Vitamin B1 (thiamine)
Vitamin B1 (riboflavin)
Vitamin B3 (niacin)
Vitamin B5 (panthothenic acid)
Vitamin B6 (pyridoxins)
Vitamin B7 (biotin)
Vitamin B9 (folic acid)
Vitamin B12 (cobalamins)
All are water soluble
Energy production
Production of genetic materials
Nervous system (produces myelin)
Production of acetylcholine
Synthesis of red blood cells
Required for many biochemical processes:
- proper energy metabolism
- immune function
- nerve function

* important in the production of several brain chemicals --> improves cognitive function, mood, energy, and sleep
Blood Cell Production
Problem: Folic Acid Deficiencies
Risk factors
Malnutrition (vitamin-poor diet)
Pregnant women
Malabsorption-related diseases
Alcohol abuse

Megaloblastic Anemia
Neural tube defects

Problem: Folic Acid Excesses
Too much may cause:
Anemia and Nerve Damage
Excess amounts of folic acid masks effects of Vitamin B12 deficiency
Worsening of Seizures
Anti-seizure meds lower absorption of folic acid
Problem: Folic Acid Deficiencies
Pale skin
Swollen tongue
Poor growth
Water soluble vitamin --> most excess folic acid is excreted in the urine
More than 1000 mcg/day = excessive amount
Blood cells: Vitamin B12 + Intrinsic Factor

Intrinsic factor: a protein made by the parietal cells in the stomach
Intrinsic factor and Vitamin B12 bind together, then are absorbed in the small intestine to aid in RBC production
Deficiency in Vitamin B12 will restrain this process
Pernicious anemia:
Autoimmune disorder where the body does not produce
Case Study
Symptoms of B12 Deficiency
-strange sensations, numbness, tingling

-difficulty walking


-difficulty thinking or memory loss

-paranoia or hallucinations

-weakness or fatigue

High-Risk Groups: Deficiency
-B12 is found almost exclusively in animal products)
-vegetarians intake a high amount of folate which may mask symptoms of B12 deficiency

-Pregnant or lactating vegan/vegetarian women should be aware that a baby can develop deficiency even if she is healthy

Vitamin B12 Excess
B12 is water soluble, so excesses are usually excreted in the urine

Elevated levels of B12 may be a sign of a serious hematological disorder

Potatoes are often broadly classified as high on the glycemic index (GI) and so are often excluded from the diets of individuals trying to follow a low-GI diet. In fact, the GI of potatoes can vary considerably depending on type (such as red, russet, white, or Prince Edward), origin (where it was grown), preparation methods (i.e., cooking method, whether it is eaten hot or cold, whether it is mashed or cubed or consumed whole, etc.), and with what it is consumed (i.e., the addition of various high-fat or high-protein toppings).

New capacity set to heighten Chinese folic acid price …

Folic acid CAS 59-30-3 | 103984 - Industrial & Lab …

Folic acid (Vitamin B9) is required in the body for the formation of red blood cells and for proper brain and immune function. It aids in the production of DNA and RNA, the body's genetic material. Folic acid is especially important when rapid synthesis of DNA is required during periods of high growth, such as infancy, adolescence and pregnancy or in tissues where cells are dividing rapidly, such as the bone marrow, digestive tract and skin tissues.

Thanks Judy for following up with this topic and your own observations…’thankyouverymuch’.
Methylation: which is hard to get your head around

Folic Acid Test: Procedure, Preparation, and Results
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I am homozygous for MTHFR 677, have pyroluria, low histamine, low homocysteine, very low triglycerides, and find that I have symptoms of both under and overmethylation. Ive never been overweight and can’t if I try! With the exception of not having seasonal allergies and having chemical and food intolerances, I seem to have more of the undermethylation symptoms. I recently learned about the pyroluria, so have been supplementing for that with mostly positive results. I don’t know what to do with the low histamine though, as I have repeatedly been intolerant to folate, despite trying in various ways (with other supps) and several times. I have a knowledgable naturopath and another practioner who have helped me, but I figured it doesn’t hurt to ask you if you might have any thoughts! It has been a very long journey and though I feel we’ve narrowed in in the causes, I’m increasing weary….. thanks for any help.

Folic Acid Deficiency #callmecha

Its more important to treat the way you feel, rather than to focus on the fact that your histamine is low. Are you still symptomatic? There are so many causes of not feeling well, like gut dysbiosis and infections, endocrine dysregulation and toxicity. If you not feel well with folate, then its not for you. I find that mind body spiritual practices make a huge difference for myself and my patients.

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Essentially, I have very strong manifestations, which are decreased with l-methylfolate 15mg qd and methylcobalamin 1mg bid. I am on numerous other medications as well.

National Collection of Industrial Microorganisms (NCIM)

Hello! I just stumbled across this page because I’m searching for answers on methylation and I have a question for you. My histamine level is 65. My practioner thinks I’m over methylated and wants me on B12. We tried hydroxy B12 and it knocked me flat. We then tried methyl B12 and it was better than the hydroxy but overall it increased my symptoms of fatigue, depression, anxiety, trichotillomania, food intolerances, vitamin/mineral intolerances. My practioner wants to add folate to the B12 but I’m scared of it. I’m starting to wonder if it could be under methylation instead. What do you think?

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