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Percutaneous aortic valve replacement - Wikipedia

Utilizes the same bovine pericardial tissue (from a cow's heart) as Edwards surgical valves

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Aortic Stenosis Prognosis | New Heart Valve HCP

Purpose: The aim of this study was to investigate our clinical experience in a contemporary series of aortic valve replacement (AVR) for aortic stenosis (AS) with or without coronary artery bypass grafting (CABG), and compare the early and mid-term results between patients aged more than 80 years and those aged less than 80 years. Methods: A retrospective review was performed of 258 consecutive patients with aortic stenosis (AS) who underwent AVR between August 2002 and December 2010 at Juntendo University Hospital. Results: Operative mortality was 7.3% in patients aged 80 years and older, compared with 3.6% in younger patients. Thus, operative mortality was higher in the older patients compared with the younger patients, but was not statistically significant between the two groups. Age more than 80 years was not a predictor of operative mortality. Advanced NYHA class (p = 0.03; odds ratio [OR], 9.5) was found to be a multivariate independent predictor of operative mortality. Patients aged 80 years and older were significantly more likely to suffer from respiratory failure after surgery than younger patients, but there were no significant differences in any other complications between the two age groups. Non-home discharge rate was significantly higher in the patients aged 80 years and older (21.9%) than in the younger patients (5.5%). Three-year survival was 84% in patients aged more than 80 years, and 83% of these elderly patients were living at home at the last follow-up. Conclusions: Patients aged 80 years and older have acceptable results of AVR with slightly increased risk of early mortality and morbidity compared with younger patients.

Results of aortic valve replacement for aortic stenosis in patients aged 80 years and older

The Edwards SAPIEN XT transcatheter heart valve, model 9300TFX, and accessories are indicated for relief of aortic stenosis in patients with symptomatic heart disease due to severe native calcific aortic stenosis who are judged by a Heart Team, including a cardiac surgeon, to be at intermediate or greater risk for open surgical therapy (i.e., predicted risk of surgical mortality ≥ 3% at 30 days, based on the Society of Thoracic Surgeons (STS) risk score and other clinical co-morbidities unmeasured by the STS risk calculator).

Transcatheter Aortic Valve Replacement (TAVR) | New …

The safety and effectiveness of the transcatheter heart valve is also not known for patients who have:

Between August 2002 and December 2010, 258 consecutive patients underwent AVR for AS at Juntendo University Hospital, including 82 patients with concomitant CABG. Patients were excluded from this cohort study if they required concomitant mitral or tricuspid valve surgery. This study was approved by the Medical Ethics Committee of Juntendo University. Baseline preoperative characteristics of this study cohort are listed in . Outcome measures included operative mortality, postoperative complications (respiratory failure, renal failure, stroke, reoperation for any reason, deep sternal wound infection, gastrointestinal complication, systemic infection, pacemaker implantation for complete atrioventricular heart block), non-home discharge, and mid-term mortality. Operative mortality was defined as death within 30 days of surgery or as death at any time before discharge from hospital. Renal failure was defined as creatinine level greater than 2 mg/dL postoperatively or new requirement for dialysis postoperatively. Respiratory failure was defined as prolonged postoperative ventilation (>24 hours) or need for reintubation or tracheostomy. Stroke was defined as a new permanent neurological event postoperatively.

In recent years, transcatheter aortic valve implantation (TAVI) has emerged as a less invasive alternative to AVR for patients with AS considered to be at very high surgical risk. However, 30-day and 1-year cumulative mortality rates after TAVI have been reported to be 3.4% to 10% and 22.1% to 24.2%, respectively [5,6], and controversy exists about whether high-risk elderly patients actually benefit from TAVI in terms of early and midterm outcomes compared with conventional AVR. Therefore, there is increasing interest in evaluation of outcomes after AVR in elderly patients. The aim of this study was to report our clinical experience in a contemporary series of AVR for AS with or without CABG, compare the early and mid-term results between patients aged more than 80 years and those aged less than 80 years, and determine the risk factors for early morbidity and mortality, non-home discharge, and mid-term mortality.

Transcatheter Aortic Valve Replacement Procedure | …

The safety and effectiveness of the transcatheter heart valve is also not known for patients who have:

These valves are intended for use in patients whose aortic valvular disease is sufficiently advanced to warrant replacement of their natural valve with a prosthetic one. It is also intended for use in patients with a previously implanted aortic valve prosthesis which is no longer functioning adequately and requires replacement. Valve replacement can include the following risks:

The valve component consists of two flat, semicircular, pyrolytic carbon-coated or polymer leaflets that pivot about struts attached to the valve housing by hinges; the synthetic polymer blood vessel is designed to conform to the aortic root anatomy and is impregnated with a bioabsorbable animal-derived gelatin.

Between heart contractions, the valve closes, preventing blood from flowing backwards into the heart.
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  • 01/10/2008 · Prosthetic valve sparing aortic root ..

    The On-X® Prosthetic Heart Valve is a bileaflet mechanical heart valve, which consists of an orifice and two leaflets.

  • Transcatheter Aortic Valve Replacement ..

    The Edwards SAPIEN 3 transcatheter heart valve and delivery system should not be used in patients who:

  • Aortic Valve Prostheses - ResearchGate

    The Edwards SAPIEN XT transcatheter heart valve and delivery systems should not be used in patients who:

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Carpentier-Edwards PERIMOUNT Aortic Heart Valve

The Edwards SAPIEN 3 transcatheter heart valve will be placed on the delivery system and compressed on a balloon. The delivery system carrying the valve will be placed through the sheath and delivered to your aortic valve. The balloon of the delivery system will be inflated, expanding the new valve within your diseased valve.

The latest advancement in transcatheter aortic valve replacement ..

Once a valve becomes sufficiently damaged, it may need to be replaced, in order to prevent heart failure and premature death.

The operation to replace an aortic valve takes 2-3 hours to perform.

Mosaic Tissue Valve Heart Valve Disease - Medtronic

The Edwards SAPIEN 3 transcatheter heart valve, model 9600TFX, and accessories are indicated for relief of aortic stenosis in patients with symptomatic heart disease due to severe native calcific aortic stenosis who are judged by a Heart Team, including a cardiac surgeon, to be at intermediate or greater risk for open surgical therapy (i.e., predicted risk of surgical mortality ≥ 3% at 30 days, based on the Society of Thoracic Surgeons (STS) risk score and other clinical co-morbidities unmeasured by the STS risk calculator).

Mosaic Tissue Valve Heart Valve Disease

This damage will cause the valve to either "leak", resulting in "aortic insufficiency" or to become "restricted" and not open fully, resulting in "aortic stenosis".

Types of Aortic Valve Replacements - Heart Home Page

The long-term durability of the Edwards SAPIEN 3 transcatheter heart valve is not known, at this time. Regular medical follow-up is recommended to evaluate how well a patient’s heart valve is performing. For patients who have previously had aortic valve replacement, the safety, effectiveness, and durability of putting a transcatheter valve in an already implanted artificial valve are not known at this time.

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